Troponin T, cardiac muscle (UniProt P45379; also known as Cardiac muscle troponin T, cTnT, TnTc) is encoded by the TNNT2 (also known as CMD1D, CMH2, RCM3) gene (Gene ID 7139) in human. Troponin is a complex composed of three regulatory proteins, troponin C, troponin I, and troponin T). Troponin is found in both skeletal muscle and cardiac muscle where it plays an integral role in muscle contraction. Troponin T (TnT) is the component that binds tropomyosin, while troponin I (TnI) binds actin in thin myofilaments to hold the actin-tropomyosin complex in place. Three tissue TnT types exist, the slow skeletal troponin T1 encoded by the TNNT1 gene, the cardiac troponin T2 encoded by the TNNT2 gene, and the fast skeletal troponin T3 encoded by the TNNT3 gene.
Synonyms: Troponin T, cardiac muscle, Cardiac muscle troponin T, cTnT, TnTc
Application: Research Sub CategoryCytoskeleton
Other Notes: Concentration: Please refer to lot specific datasheet.