Synonyms: Anti-DDF1; Anti-DKFZP434J214; Anti-DKFZp686N0351; Anti-DKFZp686P1838; Anti-TCDD-inducible poly(ADP-ribose) polymerase
Storage: -20C
Biochem Physiol Actions: TIPARP is a poly [ADP-ribose] polymerase using NAD+ as a substrate to transfer ADP-ribose onto glutamic acid residues of a protein acceptor; repeated rounds of ADP-ribosylation leads to the formation of poly(ADPribose) chains on the protein, thereby altering the function of the target protein. TIPARP may play a role in the adaptative response to chemical exposure (TCDD) and thereby mediates certain effects of the chemicals.