Synonyms: Taz Antibody; Taz Antibody - Anti-TAZ antibody produced in rabbit; Anti-Transcriptional co-activator with PDZ-binding motif
MDL No.: MFCD03792065
Storage: -20C
UNSPSC Code: 12352203
General description: Tafazzin (TAZ) is encoded by the WW domain containing transcription regulator 1 (WWTR1) gene mapped to human chromosome Xq28. The encoded protein contains 400 amino acids. It is characterized by a conserved WW domain, implicated in binding PPXY motif, a coiled-coil region associated with protein-protein interaction and a C-terminal motif involved in binding the PDZ domain.
Biochem/physiol Actions: Tafazzin (TAZ) plays a vital role in the various cellular process including cell proliferation, differentiation, apoptosis, migration, invasion, epithelial-mesenchymal transition (EMT) and stemness in multiple human cancers. TAZ associates with other transcription factors such as RUNX2 (runt-related transcription factor 2), PPAR (peroxisome proliferator-activated receptor), PAX3 and 8 (paired box gene 3 and 8) and TTF1 (thyroid transcription factor 1) and plays an essential role in osteoblastic, myogenic and adipogenic differentiation.
Immunogen: synthetic peptide corresponding to residues 386-400 of human TAZ.
Physical form: solution in phosphate buffered saline, containing 0.02% sodium azide.
RIDADR: NONH for all modes of transport
WGK Germany: nwg