Synonyms: Anti-SP
MDL No.: MFCD00162870
Storage: -20C
UNSPSC Code: 12352203
General description: Substance P (SP) is a 11 amino acid peptide. It is a member of tachykinins family, that includes neurokinin A, neurokinin B, neuropeptide K, neuropeptide Y and hemokinin-1 It is located on human chromosome 7q21.3.
Application: Anti-Substance P antibody has been used in immunostaining and immunohistochemistry.
Biochem/physiol Actions: Substance P (SP) improves the multiplication and paracrine ability of stem cells acquired from adipose in vitro. It participates in the movement of several organ tracts, trigger glandular secretion and controls autonomic reflexes. It plays an important role in neuroimmune and systemic autoimmune/inflammatory conditions like multiple sclerosis (MS), rheumatoid arthritis, inflammatory bowel disease and also in infections and cancer.
Immunogen: synthetic Substance P (SP), conugated to KLH.
Analysis Note: The antiserum is evaluated for activity and specificity by dot blot immunoassay and RIA.
RIDADR: NONH for all modes of transport
WGK Germany: 3