STRN3 (striatin 3) belongs to the striatin sub-family of WD-40 repeat proteins. It is involved in a wide range of physiological processes including signal transduction, cell cycle progression and protein-protein interactions. Structurally, it is composed of six WD-40 repeats containing motif at the C-terminal end and a transcriptional activator region at the N-terminal end.
Synonyms: Anti-Cell-cycle autoantigen SG2NA antibody produced in rabbit; Anti-S/G2 antigen antibody produced in rabbit; Anti-Striatin-3 antibody produced in rabbit
Storage: -20C
Application: All Prestige Antibodies Powered by Atlas Antibodies are developed and validated by the Human Protein Atlas (HPA) project (www.proteinatlas.org)and as a result, are supported by the most extensive characterization in the industry. The Human Protein Atlas project can be subdivided into three efforts: Human Tissue Atlas, Cancer Atlas, and Human Cell Atlas. The antibodies that have been generated in support of the Tissue and Cancer Atlas projects have been tested by immunohistochemistry against hundreds of normal and disease tissues and through the recent efforts of the Human Cell Atlas project, many have been characterized by immunofluorescence to map the human proteome not only at the tissue level but now at the subcellular level. These images and the collection of this vast data set can be viewed on the Human Protein Atlas (HPA) site by clicking on the Image Gallery link. To view these protocols and other useful information about Prestige Antibodies and the HPA, visit sigma.com/prestige.
Biochem Physiol Actions: STRN3 (striatin 3) is highly interactive to various proteins including caveolin and calmodulin. By this protein-protein interaction, it promotes the formation of a multimeric protein unit called striatin-interacting phosphatase and kinase.
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