Stomatin-like protein 3 (STOML3) is expressed in olfactory sensory neurons and is localized in lipid rafts. It belongs to the stomatin-family of proteins and contains a stomatin signature domain. The gene encoding this protein is localized on chromosome 13q13.3.
Synonyms: Anti-Stomatin-like protein 3
Storage: -20C
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Biochem Physiol Actions: Stomatin-like protein 3 (STOML3) may be involved in modulating odorant signals in the lipid rafts of olfactory cilia. It has been shown to be associated with proteins like adenylate cyclase III (ACIII) and caveolin-1 in lipid rafts. STOML3 interacts with stomatin and acid-sensing (proton-gated) ion channel (ASIC) subunits, and regulates them. STOML3 vesicles are suggested to be involved in targeting of mechanotransduction complexes into the peripheral terminals of sensory neurons.
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