The gene SRRM3 (serine/arginine repetitive matrix protein 3) is mapped to human chromosome 7q11.23.
Synonyms: Anti-AC005077.11 antibody produced in rabbit; Anti-SRRM2-like protein
Storage: -20C
Application: All Prestige Antibodies Powered by Atlas Antibodies are developed and validated by the Human Protein Atlas (HPA) project (www.proteinatlas.org)and as a result, are supported by the most extensive characterization in the industry. The Human Protein Atlas project can be subdivided into three efforts: Human Tissue Atlas, Cancer Atlas, and Human Cell Atlas. The antibodies that have been generated in support of the Tissue and Cancer Atlas projects have been tested by immunohistochemistry against hundreds of normal and disease tissues and through the recent efforts of the Human Cell Atlas project, many have been characterized by immunofluorescence to map the human proteome not only at the tissue level but now at the subcellular level. These images and the collection of this vast data set can be viewed on the Human Protein Atlas (HPA) site by clicking on the Image Gallery link. To view these protocols and other useful information about Prestige Antibodies and the HPA, visit sigma.com/prestige.
Biochem Physiol Actions: SRRM3 (serine/arginine repetitive matrix protein 3) is suggested to be involved in alternative splicing. It is responsible for processing of alternatively spliced REST (RE1-silencing transcription factor) transcript, REST-003, into non-coding RNAs. REST-003 participates in regulation of breast cancer invasiveness.
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