Synonyms: Anti-LAT2; Anti-LPI-PC1; Anti-Solute carrier family 7 (cationic amino acid transporter, y+ system), member 8
Storage: -20C
Application: Anti-SLC7A8 antibody produced in rabbit is suitable for western blotting at a concentration of 1.25mug/ml.
Biochem Physiol Actions: SLC7A8 also referred to as LAT2 is an L-type neutral amino acid transporter present in the epithelium of kidney proximal tubules and the digestive tract. LAT2 preferentially selects branched-chain amino acids as substrates and transports them across membranes. It has been reported that LAT2 activates the pathway mediated by mammalian target of rapamycin complex 1 (mTORC1) in the glomerular epithelial cells and has a role in the pathogenesis of crescentic glomerulonephritis.