Synonyms: Anti-FLJ20551; Anti-FLJ22703; Anti-Solute carrier family 25, member 38
Storage: -20C
Application: Anti-SLC25A38 antibody produced in rabbit is suitable for western blotting at a concentration of 0.25mug/ml and for immunohistochemistry of paraffin-embedded tissue sections at a concentration of 4-8mug/ml.
Biochem Physiol Actions: SLC25A38 belongs to the mitochondrial carrier family and is essential for the biosynthesis of heme during erythropoiesis. Mutations in the gene encoding this carrier protein result in erythroblast mitochondrial iron overload, characteristic of congenital sideroblastic anemias. SLC25A38 is overexpressed in acute lymphoblastic lymphoma and may be considered as a diagnostic marker.