Peptide transporter 1 (PepT 1), also known as solute carrier family 15 member 1 (SLC15A1), is a protein encoded by SLC15A1 gene in humans. It is a di/tripeptide transporter protein highly expressed in the intestinal brush border membrane and not expressed in colons. It has been predicted that the ~78,810kDa transporter protein consists of 708 amino acid residues and 12 putative membrane-spanning domains.
Synonyms: Anti-Intestinal H(+; Anti-Oligopeptide transporter, small intestine isoform; Anti-Solute carrier family 15 member 1
Storage: -20C
Application: All Prestige Antibodies Powered by Atlas Antibodies are developed and validated by the Human Protein Atlas (HPA) project (www.proteinatlas.org)and as a result, are supported by the most extensive characterization in the industry. The Human Protein Atlas project can be subdivided into three efforts: Human Tissue Atlas, Cancer Atlas, and Human Cell Atlas. The antibodies that have been generated in support of the Tissue and Cancer Atlas projects have been tested by immunohistochemistry against hundreds of normal and disease tissues and through the recent efforts of the Human Cell Atlas project, many have been characterized by immunofluorescence to map the human proteome not only at the tissue level but now at the subcellular level. These images and the collection of this vast data set can be viewed on the Human Protein Atlas (HPA) site by clicking on the Image Gallery link. To view these protocols and other useful information about Prestige Antibodies and the HPA, visit sigma.com/prestige.
Biochem Physiol Actions: Solute carrier family 15 member 1 (SLC15A1) is majorly involved in protein absorption in the human intestine. During chronic inflammation, its expression is induced in the colon. Tri-DAP transport may occur more effectively during such conditions, contributing to intestinal inflammation.
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