Synonyms: Anti-FKSG84; Anti-PRO0899; Anti-TDE2; Anti-TDE2L; Anti-serine incorporator 2
Storage: -20C
Application: All Prestige Antibodies Powered by Atlas Antibodies are developed and validated by the Human Protein Atlas (HPA) project (www.proteinatlas.org)and as a result, are supported by the most extensive characterization in the industry. The Human Protein Atlas project can be subdivided into three efforts: Human Tissue Atlas, Cancer Atlas, and Human Cell Atlas. The antibodies that have been generated in support of the Tissue and Cancer Atlas projects have been tested by immunohistochemistry against hundreds of normal and disease tissues and through the recent efforts of the Human Cell Atlas project, many have been characterized by immunofluorescence to map the human proteome not only at the tissue level but now at the subcellular level. These images and the collection of this vast data set can be viewed on the Human Protein Atlas (HPA) site by clicking on the Image Gallery link. To view these protocols and other useful information about Prestige Antibodies and the HPA, visit sigma.com/prestige.
Biochem Physiol Actions: SERINC2 is referred as TDE2, TDE2L, FKSG84 and PRO0899. It may have an effect on tumor cell growth by influencing the expression of SREBP and p21. This gene possess sequence similarity to the mouse testicular tumor-differentially-expressed (Tde1/MUSTETU) gene and is observed in NSCLC. It is replicable and is significantly a risk gene specific for alcohol dependence in individuals of European descent.
Legal Information: Prestige Antibodies is a registered trademark of Sigma-Aldrich Co. LLC