Synonyms: HSEC61; SEC61; SEC61A; SEC61A1
Storage: -20C
UNSPSC Code: 12352203
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Application: Suggested starting dilutions are as follows: ICC/IF: 1:100-1:1000, IHC-P: 1:100-1:1000, WB: 1:500-1:3000. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user.
Biochem/physiol Actions: The protein encoded by this gene belongs to the SECY/SEC61- alpha family. It appears to play a crucial role in the insertion of secretory and membrane polypeptides into the endoplasmic reticulum. This protein found to be tightly associated with membrane-bound ribosomes, either directly or through adaptor proteins. This gene encodes an alpha subunit of the heteromeric SEC61 complex, which also contains beta and gamma subunits. [provided by RefSeq]
Immunogen: Synthetic peptide containing a sequence corresponding to a region within amino acids 413 and 426 (P61619) of SEC61A1 according to NP_037468
Physical form: 1XPBS, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
RIDADR: NONH for all modes of transport
WGK Germany: 1