Severe acute respiratory syndrome (SARS) is a viral respiratory illness caused by a coronavirus, called SARS-associated coronavirus (SARS-CoV). Human coronaviruses (HCoVs) were previously only associated with mild diseases. The SARS-CoV genome contains five major open reading frames (ORFs) that encode the replicase polyprotein; the spike (S), envelope (E), and membrane (M) glycoproteins; and the nucleocapsid protein (N). It is an enveloped, positive-sense, single-stranded RNA virus.
Application: Anti-SARS Antibody, S Specific, clone 154C is suitable for the detection of SARS in:
•Immunofluorescence
•ELISA
•Western Blot
•Immunoblot
•NeutralizationOptimal dilutions must be determined by the end user.Research CategoryInfectious DiseasesResearch Sub CategoryInfectious Diseases - Viral
Biochem Physiol Actions: Severe acute respiratory syndrome (SARS) -associated coronavirus' (SARS-CoV) spike glycoprotein mediates the viral entry by binding to the host cell receptor. SARS spike protein is the target for vaccine development and antibody therapies.
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Other Notes: Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.