Synonyms: Anti-MGC111543 antibody produced in rabbit; Anti-MIG5 antibody produced in rabbit; Anti-TC-25 antibody produced in rabbit; Anti-p21-Rac1 antibody produced in rabbit; Anti-ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) antibody produced in rabbit
MDL No.: MFCD01322704
Storage: -20C
UNSPSC Code: 12352203
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General description: RAC1 (ras-related C3 botulinum toxin substrate 1) is a polarity related protein , that belongs to the Rho family of small guanosine triphosphatases. It is located on human chromosome 7p22.
Application: Anti-RAC1 (Ab-71) antibody has been used in western blot analysis .
Biochem/physiol Actions: RAC1 (ras-related C3 botulinum toxin substrate 1) plays a major role in cancer invasion and metastasis. It can be considered as a therapeutic target for breast cancer. It is essential for several cellular activities like phagocytosis, adhesion, migration, motility, cell proliferation and axonal growth.
Immunogen: Peptide sequence around aa. 69-73 (P-L-S-Y-P), according to the protein RAC1.
Physical form: Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol
Target description: Rac1 encoded by this gene is a GTPase which belongs to the RAS superfamily of small GTP-binding proteins. Members of this superfamily appear to regulate a diverse array of cellular events, including the control of cell growth, cytoskeletal reorganization, and the activation of protein kinases. Two transcript variants encoding different isoforms have been found for this gene.
RIDADR: NONH for all modes of transport
WGK Germany: 1