POU2F3, also known as Skn-1a and OCT11, gene is mapped to human chromosome 11q23.3. The gene codes for a keratinocyte-specific POU transcription factor. The protein is expressed in stratified squamous epithelia, including the epidermis, cervix and foreskin.
Synonyms: Anti-POU domain, class 2, transcription factor 3
Storage: -20C
Application: Rabbit Anti-POU2F3 antibody can be used for western blotting applications at a concentration of 0.5mug/ml. It can also be used for IHC assays at 4-8mug/ml, using paraffin-embedded tissues.
Biochem Physiol Actions: POU2F3 is a transcription factor that is involved in the growth and differentiation of keratinocytes. Studies have reported that Pou2f3 (Skn-1a) is involved in the differentiation of chemosensory cells. Furthermore, this transcription factor is also required for specifying the lineage of taste receptor cells.