The phospholipase A2 group XV (PLA2G15) gene is mapped to human chromosome 16q22.1. The encoded protein with a molecular weight of 45kDa is assumed to be associated with high-density lipoprotein. PLA2G15 is expressed in exosomes.
Synonyms: Anti-Gxvpla2; Anti-Llpl; Anti-Lypla3; Anti-Phospholipase a2, group xv
Storage: -20C
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Biochem Physiol Actions: Phospholipase A2 group XV (PLA2G15) codes for lysophospholipase enzyme, which catalyzes regulation of the multifunctional lysophospholipids. In addition, the encoded protein also hydrolyzes lysophosphatidylcholine to glycerophosphorylcholine and a free fatty acid. Deficiency of PLA2G15 might lead to phospholipidosis.
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