AKT1 (AKT serine/threonine kinase 1) is also called as v-akt murine thymoma viral oncogene homolog 1 and PKB a (protein kinase B). It is expressed in liver,muscle and adipocytes. AKT1 gene is mapped to human chromosome 14q32. It is a member of AKT family that has an amino-terminal pleckstrin homology (PH) domain, a short a helical linker and a carboxyl-terminal kinase domain.
Synonyms: phosphorylation at Ser473
Storage: -20C
Biochem Physiol Actions: AKT1 (AKT serine/threonine kinase 1) controls the survival of cells and anti-apoptotic actions that attack the pathogenesis of several cancers, hence it plays a crucial role in tumorigenesis. In mice, AKT1 is essential for normal development.