Synonyms: Anti-3-oxoacid-CoA transferase 1; Anti-Scot-S; Anti-Somatic-type succinyl CoA:3-oxoacid CoA-transferase; Anti-Succinyl-CoA:3-ketoacid-coenzyme A transferase 1, mitochondrial
Storage: -20C
Application: Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.Immunohistochemistry (1 paper)
Biochem Physiol Actions: OXCT1 (3-oxoacid CoA transferase 1) is a mitochondrial ketolytic enzyme involved in the ketone metabolism. It facilitates the conversion of coenzyme A from succinyl-coenzyme A to acetoacetate for the generation of acetoacetyl-CoA. It has been reported that the transfer reaction may utilize glucose for the energy requirement. Missense mutations in OXCT1 cause succinyl CoA:3-oxoacid CoA transferase deficiency.
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