Nudix hydrolase 16 like 1 (NUDT16L1) also known as TIRR (tudor interacting repair regulator), specifically interacts with the ionizing radiation induced foci formation (IRIF) region of P53 binding protein 1 (53BP1). The gene is located on human chromosome 16p13.3. The protein is a member of nucleoside diphosphate-linked moiety X (Nudix) hydrolases family.
Synonyms: Anti-Nudix (Nucleoside Diphosphate Linked Moiety X)-Type Motif 16-Like 1; Anti-SDOS
Storage: -20C
Application: Anti-NUDT16L1 antibody produced in rabbit has been used in western blotting and immunoprecipitation.
Biochem Physiol Actions: Nudix hydrolase 16 like 1 (NUDT16L1) acts as an inhibitor of P53 binding protein 1 (53BP1). The protein repairs double strand breaks by masking the histone methyl-lysine binding function of P53 binding protein 1 (53BP1).
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