NRXN3 (neurexin 3) is a neuronal cell surface protein, also expressed in the lung, pancreas, heart, placenta, liver and kidney. In humans, three types of neurexin genes are present i.e. NRXN1, NRXN2, and NRXN3. It belongs to the family of polymorphic cell-surface proteins.
Synonyms: Anti-Neurexin 3 isoform alpha precursor antibody produced in rabbit
Storage: -20C
Application: All Prestige Antibodies Powered by Atlas Antibodies are developed and validated by the Human Protein Atlas (HPA) project (www.proteinatlas.org)and as a result, are supported by the most extensive characterization in the industry. The Human Protein Atlas project can be subdivided into three efforts: Human Tissue Atlas, Cancer Atlas, and Human Cell Atlas. The antibodies that have been generated in support of the Tissue and Cancer Atlas projects have been tested by immunohistochemistry against hundreds of normal and disease tissues and through the recent efforts of the Human Cell Atlas project, many have been characterized by immunofluorescence to map the human proteome not only at the tissue level but now at the subcellular level. These images and the collection of this vast data set can be viewed on the Human Protein Atlas (HPA) site by clicking on the Image Gallery link. To view these protocols and other useful information about Prestige Antibodies and the HPA, visit sigma.com/prestige.
Biochem Physiol Actions: NRXN3 (neurexin 3) is mainly involved in the intercellular signaling pathways and neuronal cell adhesion during synaptogenesis. It participates in different intercellular connections with the help of extracellular matrix protein and other proteins. The gene may play a role in schizophrenia, autism and obesity.
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