Nuclear factor I/B (NFIB) belongs to the nuclear factor one family of transcription factors. This gene is mapped to human chromosome 9p24.1.
Synonyms: Anti-CCAAT-box-binding transcription factor; Anti-CTF; Anti-NF-I/B; Anti-NF1-B; Anti-NFI-B; Anti-Nuclear factor 1 B-type; Anti-Nuclear factor 1/B; Anti-TGGCA-binding protein
Storage: -20C
Application: Anti-NFIB antibody produced in rabbit has been used in:
• immunohistochemistry
•chromatin immunoprecipitation (ChIP)
•co-immunoprecipitation and immunohistochemistry
•immunoblotting
Biochem Physiol Actions: Nuclear factor I/B (NFIB) participates in the development of embryos, maintenance of stem cell activity, modulation of cell differentiation and tumor related activities. This transcription factor plays a key role in tumor progression. It is also implicated in glioma
• In pleomorphic adenomas, NFIB gene is considered as a translocation partner gene.
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