Neurofilament 200 is encoded by the gene located at human chromosome 22q12.2.
Storage: -20C
Application: Anti-Neurofilament 200 (Phos and Non-Phos) antibody has been used in
•immunoblotting
•immunofluorescence
•immunohistochemistry
Biochem Physiol Actions: Neurofilament 200 has an important function in axonal transport, axonal plasticity and maintaining the structure of neuronal cytoskeleton. Defects in Neurofilament 200 are a cause of susceptibility to amyotrophic lateral sclerosis (ALS) and these accumulations are a hallmark of pathological lesion.