N-myc downstream regulated 1 (NDRG1) is a cytoplasmic hydrolase that modulates stress, hormonal responses, cell growth, differentiation and LDL receptor trafficking. It mediates antimetastatic effects in cancer cells and is downregulated in prostate cancer cells.Rabbit Anti-NDRG1 antibody recognizes canine, chicken, mouse, zebrafish, bovine, human, and rat NDRG1.
Synonyms: Anti-CAP43; Anti-CMT4D; Anti-DRG1; Anti-GC4; Anti-HMSNL; Anti-N-Myc downstream Regulated gene 1; Anti-NDR1; Anti-NMSL
Storage: -20C
Application: Rabbit Anti-NDRG1 antibody is suitable for western blot applications at a concentration of western blot applications at a concentration of 2.5 mug/ml.
Biochem Physiol Actions: NDRG1 is a member of the N-myc downregulated protein family which belongs to the alpha/beta hydrolase superfamily. NDRG1 is a cytoplasmic protein involved in stress responses, hormone responses, cell growth, and differentiation. Mutation in its gene has been reported to be causative for hereditary motor and sensory neuropathy-Lom.This gene is a member of the N-myc downregulated gene family which belongs to the alpha/beta hydrolase superfamily. The protein encoded by this gene is a cytoplasmic protein involved in stress responses, hormone responses, cell growth, and differentiation. Mutation in this gene has been reported to be causative for hereditary motor and sensory neuropathy-Lom.