N-(a)-acetyltransferase 60, NatF catalytic subunit (NAA60) is encoded by the gene mapped to human chromosome 16p13.3. The encoded protein is predominantly expressed in Golgi. hNaa60 is characterized by a unique amphipathic a-helix (a5) and GNAT domain that might facilitate Golgi localization of this protein.
Synonyms: Anti-FLJ14154; Anti-NAT15
Storage: -20C
Application: All Prestige Antibodies Powered by Atlas Antibodies are developed and validated by the Human Protein Atlas (HPA) project (www.proteinatlas.org)and as a result, are supported by the most extensive characterization in the industry. The Human Protein Atlas project can be subdivided into three efforts: Human Tissue Atlas, Cancer Atlas, and Human Cell Atlas. The antibodies that have been generated in support of the Tissue and Cancer Atlas projects have been tested by immunohistochemistry against hundreds of normal and disease tissues and through the recent efforts of the Human Cell Atlas project, many have been characterized by immunofluorescence to map the human proteome not only at the tissue level but now at the subcellular level. These images and the collection of this vast data set can be viewed on the Human Protein Atlas (HPA) site by clicking on the Image Gallery link. To view these protocols and other useful information about Prestige Antibodies and the HPA, visit sigma.com/prestige.
Biochem Physiol Actions: N-(a)-acetyltransferase 60, NatF catalytic subunit (NAA60) acts as an organelle N-terminal acetyltransferase and catalyzes the Nt-acetylation of transmembrane proteins. The encoded protein plays a vital role in maintaining Golgi's structural integrity. NAA60 acetylates free histone H4 and aids in chromatin assembly.
Legal Information: Prestige Antibodies is a registered trademark of Sigma-Aldrich Co. LLC