Synonyms: Anti-165 kDa connectin-associated protein antibody produced in rabbit; Anti-165 kDa titin-associated protein antibody produced in rabbit; Anti-M-protein antibody produced in rabbit; Anti-Myomesin-2 antibody produced in rabbit
Storage: -20C
Application: All Prestige Antibodies Powered by Atlas Antibodies are developed and validated by the Human Protein Atlas (HPA) project (www.proteinatlas.org)and as a result, are supported by the most extensive characterization in the industry. The Human Protein Atlas project can be subdivided into three efforts: Human Tissue Atlas, Cancer Atlas, and Human Cell Atlas. The antibodies that have been generated in support of the Tissue and Cancer Atlas projects have been tested by immunohistochemistry against hundreds of normal and disease tissues and through the recent efforts of the Human Cell Atlas project, many have been characterized by immunofluorescence to map the human proteome not only at the tissue level but now at the subcellular level. These images and the collection of this vast data set can be viewed on the Human Protein Atlas (HPA) site by clicking on the Image Gallery link. To view these protocols and other useful information about Prestige Antibodies and the HPA, visit sigma.com/prestige.
Biochem Physiol Actions: Myomesin 2 (MYOM2) is a 165kDa structural component of sarcomeric myofibrils, also known as M-protein. It belongs to the intracellular group of the immunoglobulin superfamily of proteins and associates with the giant protein, titin, that is present in striated muscles and myosin. It has been reported that in striated muscle, MYOM2 plays a major role as a structural component of the M-band. Its expression is regulated through mammalian muscle development.
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