Synonyms: Anti-Cellular myosin heavy chain, type A antibody produced in rabbit; Anti-Myosin heavy chain 9 antibody produced in rabbit; Anti-Myosin heavy chain, nonmuscle IIa antibody produced in rabbit; Anti-Myosin-9 antibody produced in rabbit; Anti-NMMHC II-a antibody produced in rabbit; Anti-NMMHC-A antibody produced in rabbit; Anti-NMMHC-IIA antibody produced in rabbit; Anti-Nonmuscle myosin heavy chain IIa antibody produced in rabbit; Anti-Nonmuscle myosin heavy chain-A antibody produced in rabbit
Storage: -20C
Application: Anti-MYH9 antibody produced in rabbit, a Prestige Antibody, is developed and validated by the Human Protein Atlas (HPA) project (www.proteinatlas.org). Each antibody is tested by immunohistochemistry against hundreds of normal and disease tissues. These images can be viewed on the Human Protein Atlas (HPA) site by clicking on the Image Gallery link. The antibodies are also tested using immunofluorescence and western blotting. To view these protocols and other useful information about Prestige Antibodies and the HPA, visit sigma.com/prestige.
Biochem Physiol Actions: Myosin, heavy chain 9, non-muscle is a protein encoded by the MYH9 gene in humans and is mapped to chromosome 22q11.2. The gene encodes for the nonmuscle myosin heavy chain IIA. Mutation in this gene may cause autosomal dominant disorders such as Epstein syndrome, Sebastian syndrome, Fechthner syndrome and May-Hegglin anomaly (characterized by thrombocytopenia with giant platelets, inclusion bodies in granulocytes and variable levels of deafness, disturbances of vision and renal function impairment).
Legal Information: Prestige Antibodies is a registered trademark of Sigma-Aldrich Co. LLC