Synonyms: HRP
Storage: 2-8C
UNSPSC Code: 12352203
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General description: Immunoglobulin G (IgG) is part of the immunoglobulin family. It consists of a +¦ heavy chain in the constant (C) region and is widely expressed in the serum. IgG is a monomer of 150kDa and possesses two identical heavy chains and two identical light chains with molecular weight of 50kDa and 25kDa, respectively. The primary structure of this antibody also contains disulfide bonds involved in linking the two heavy chains, linking the heavy and light chains and resides inside the chains. Maternal IgG is the only antibody transported across the placenta to the fetus. It passively immunizes the infants. IgG is further subdivided into four classes namely, IgG1, IgG2, IgG3, and IgG4 with different heavy chains, named +¦1, +¦2, +¦3, and +¦4, respectively. IgG2 is involved in immune responses to bacterial capsular polysaccharide antigens. Its deficiency has been linked to an increased susceptibility to bacterial infections.
Immunogen: Mouse IgG2a heavy chain
Physical form: Supplied in 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 with 10 mg/mL Bovine Serum Albumin (BSA) - Immunoglobulin and Protease free
Physical properties: Antibody format: IgG
Reconstitution: Reconstitute with 1.0 mL deionized water (or equivalent).
Specificity: This product was prepared from monospecific antiserum by immunoaffinity chromatography using Mouse IgG coupled to agarose beads followed by solid phase adsorption(s) to remove any unwanted reactivities. Assay by immunoelectrophoresis resulted in a single precipitin arc against Anti-Peroxidase, Anti-Rabbit Serum, Mouse IgG and Mouse Serum. Specificity was confirmed by ELISA at less than 1% cross reactivity against other Mouse or heavy or light chain isotypes.
RIDADR: NONH for all modes of transport
WGK Germany: 3
Symbol: GHS07
Signal Word: Warning
Hazard Statements: H317
Precautionary statements: P280