Synonyms: HRP
Storage: 2-8C
UNSPSC Code: 12352203
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General description: Immunoglobulin G (IgG) belongs to the immunoglobulin family and is a widely expressed serum antibody. It consists of a +¦ heavy chain in the constant (C) region. The monomeric 150kDa structure of IgG constitutes two identical heavy chains and two identical light chains with molecular weight of 50kDa and 25kDa, respectively. The primary structure of this antibody also contains disulfide bonds involved in linking the two heavy chains, linking the heavy and light chains and resides inside the chains. Maternal IgG is the only antibody transported across the placenta to the fetus. It passively immunizes the infants. IgG is further subdivided into four classes namely, IgG1, IgG2, IgG3, and IgG4 with different heavy chains, named +¦1, +¦2, +¦3, and +¦4, respectively. IgG1 is induced due to antibody responses to membrane proteins and soluble protein antigens. It is the most abundant subclass of IgG.
Application: Anti-Mouse IgG1 (+¦-chain specific)-Peroxidase antibody produced in rabbit has been used in immunohistochemistry and Western blotting.
Immunogen: Mouse IgG1 heavy chain
Physical form: Supplied in 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 with 10 mg/mL Bovine Serum Albumin (BSA) - Immunoglobulin and Protease free
Physical properties: Antibody format: IgG
Reconstitution: Reconstitute with 1.0 mL deionized water (or equivalent).
Specificity: This product was prepared from monospecific antiserum by immunoaffinity chromatography using Mouse IgG coupled to agarose beads followed by solid phase adsorption(s) to remove any unwanted reactivities. Assay by immunoelectrophoresis resulted in a single precipitin arc against Anti-Peroxidase, Anti-Rabbit Serum, Mouse IgG and Mouse Serum. Specificity was confirmed by ELISA against other Mouse or Human heavy chain isotypes. Cross reactivity with Mouse IgG2b and IgG3 is negligible (<0.5 %). cross reactivity with mouse igg2a and igm is minimal.<>
RIDADR: NONH for all modes of transport
WGK Germany: 3
Symbol: GHS07
Signal Word: Warning
Hazard Statements: H317
Precautionary statements: P280