MT1-MMP plays an important role during endothelial cell migration and matrix remodeling. Although the role of MT1-MMP in endothelial cell motility is not fully characterized, its activity appears to modulate endothelial migration, invasion, and formation of capillary tubes during the angiogenic response (Galvez, 2001). Mt1-MMP also appears to play a key role in monocyte revruitment during inflammation (Salomon, 2005).
Synonyms: MT1-MMP
Storage: 2-8C
Application: Western Blot Immunohistochemistry: Frozen and paraffin-embedded tissues Immunofluorescence Flow Cytometry Blocking: 10-15mug/mL Optimal working dilutions must be determined by the end user.
Legal Information: CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Other Notes: Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.