Synonyms: MLLT3 Antibody - Anti-MLLT3 antibody produced in rabbit; Mllt3 Antibody; Anti-ALL1 fused gene from chromosome 9 protein antibody produced in rabbit; Anti-Myeloid/lymphoid or mixed-lineage leukemia translocated to chromosome 3 protein antibody produced in rabbit; Anti-Protein AF-9 antibody produced in rabbit; Anti-YEATS domain-containing protein 3 antibody produced in rabbit
Storage: -20C
Application: All Prestige Antibodies Powered by Atlas Antibodies are developed and validated by the Human Protein Atlas (HPA) project (www.proteinatlas.org)and as a result, are supported by the most extensive characterization in the industry. The Human Protein Atlas project can be subdivided into three efforts: Human Tissue Atlas, Cancer Atlas, and Human Cell Atlas. The antibodies that have been generated in support of the Tissue and Cancer Atlas projects have been tested by immunohistochemistry against hundreds of normal and disease tissues and through the recent efforts of the Human Cell Atlas project, many have been characterized by immunofluorescence to map the human proteome not only at the tissue level but now at the subcellular level. These images and the collection of this vast data set can be viewed on the Human Protein Atlas (HPA) site by clicking on the Image Gallery link. To view these protocols and other useful information about Prestige Antibodies and the HPA, visit sigma.com/prestige.
Biochem Physiol Actions: MLLT3 (myeloid/lymphoid or mixed-lineage leukemia; translocated to, 3) is associated with super elongation complex (SEC) to stimulate catalysis of RNA polymerase II transcription elongation at different regions of the DNA. This further induces oncogenic transformation. It act as a candidate regulator of erythroid/megakaryocytic (E/Meg) lineage mechanism.
Legal Information: Prestige Antibodies is a registered trademark of Sigma-Aldrich Co. LLC