The gene METTL14 (methyltransferase like 14) is mapped to human chromosome 4q. It is a homologue of METTL3. The protein has an N-terminal a-helical motif (NHM), methyltransferase domain and a C-terminal motif.
Synonyms: Anti-KIAA1627; Anti-Methyltransferase like 14
Storage: -20C
Application: Anti-METTL14 antibody produced in rabbit has been used in:
•cross-linking and RNA immunoprecipitation (CLIP)
•western blot
•immunohistochemical analysis
Biochem Physiol Actions: METTL14 mutation reduces m6A methylation in ~70% of endometrial tumors.
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