Monoamine oxidase (MAO) is localized in the outer mitochondrial membrane. It exists in two forms MAOA and MAOB. It is expressed in specific zone of brain i.e. hypothalamus, hippocampus, brain stem and olfactory bulb.
Synonyms: Anti-Amine oxidase [flavin-containing] B; Anti-MAO-B; Anti-Monoamine oxidase type B
Storage: -20C
Application: Anti-MAOB antibody produced in rabbit has been used for immunostaining and immunohistochemistry.
Biochem Physiol Actions: MAOB (monoamine oxidase B) is involved in the oxidative metabolism of neurotransmitters and dietary amines, such as dopamine, neuroactive, vasoactive amines and the Parkinsonism-producing neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP). It forms H2O2 during dopamine metabolism. It is associated with the cause of Parkinson's disease (PD).
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