Synonyms: Anti-1-Acylglycerophosphocholine O-acyltransferase 1; Anti-AYTL2; Anti-Acyltransferase-like 2; Anti-Lung-type acyl-CoA:lysophosphatidylcholine acyltransferase 1; Anti-Lysophosphatidylcholine acyltransferase 1; Anti-Phosphonoformate immuno-associated protein 3
Storage: -20C
Application: Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.Immunohistochemistry (1 paper)
Biochem Physiol Actions: LPCAT1 (lysophosphatidylcholine acyltransferase 1) is a phospholipase that plays a major role in phospholipid remodeling. During remodeling, it converts acyl-CoA to lyso-phosphatidyl choline, by transferring fatty acids for the reconstitution of phosphatidyl choline (PC). The de-acylation and re-acylation by a lyso-PC acyl transferase is supported by LPCAT1 through the Land's cycle. In addition, the protein expression has been found on the surface of lipid droplets, where it plays an important role in PC biosynthesis. It has been reported that LPCAT1 may play an essential role in cancer cell proliferation, migration, and invasion.
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