Synonyms: Anti-Ligase I, DNA, ATP-dependent; Anti-MGC117397; Anti-MGC130025
Storage: -20C
Application: Anti-LIG1 antibody produced in rabbit is suitable for western blotting at a concentration of 1mug/mL.
Biochem Physiol Actions: LIG1 gene encodes an enzyme that belongs to ATP-dependent DNA ligase protein family. The protein plays a crucial role in sealing the nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair. Mutation or defects in LIG1 gene results in Bloom's syndrome cells.