Synonyms: Anti-EZF; Anti-GKLF; Anti-Kruppel-like factor 4
Storage: -20C
UNSPSC Code: 12352203
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General description: Krüppel-like factor 4 (KLF4) is a transcription factor. It can act both as a transcriptional activator or repressor. The gene encoding this protein is localized on human chromosome 9q31.2.
Biochem/physiol Actions: Krüppel-like factor 4 (KLF4) is involved in cell growth, proliferation and differentiation in the colon. It is down-regulated in both mouse and human colonic adenomas. The protein has been implicated as a tumor suppressor in the gut, whereas in breast cancer, KLF4 is an oncogene. It is also involved in reprogramming differentiated cells into pluripotent stem cells.
Immunogen: KLF4 (NP_004226.3, )This antibody is generated from rabbits immunized with a his tag recombinant protein of human KLF4.
Physical form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
RIDADR: NONH for all modes of transport
WGK Germany: nwg