Potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4, KCNN4, is a component of a potassium channel activated by calcium. It is critically involved in calcium ion transport and cell homeostasis.
Synonyms: Anti-IK1; Anti-IKCA1; Anti-KCA4; Anti-KCa3.1; Anti-SK4; Anti-Small conductance calcium-activated channel, subfamily N, member 4; Anti-hIKCa1; Anti-hKCa4
Storage: -20C
Application: Anti-KCNN4 antibody produced in rabbit has been used in:
•western blot analysis
•immunofluorescence
•staining
•immunohistochemistry
Biochem Physiol Actions: KCNN4 (potassium calcium-activated channel subfamily N member 4) is part of a potentially heterotetrameric voltage-independent potassium channel that is activated by intracellular calcium. Activation is followed by membrane hyperpolarization, which promotes calcium influx. KCNN4 may be part of the predominant calcium-activated potassium channel in T-lymphocytes. Activation is followed by membrane hyperpolarization, which promotes calcium influx. The encoded protein may be part of the predominant calcium-activated potassium channel in T-lymphocytes. This gene is similar to other KCNN family potassium channel genes, but it differs enough to possibly be considered as part of a new subfamily.