Synonyms: Anti-IMP dehydrogenase 2 antibody produced in rabbit; Anti-IMPD 2 antibody produced in rabbit; Anti-IMPDH-II antibody produced in rabbit; Anti-Inosine-5'-monophosphate dehydrogenase 2 antibody produced in rabbit
Storage: -20C
Application: Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.Western Blotting (1 paper)
Biochem Physiol Actions: IMPDH2 (inosine 5'-monophosphate dehydrogenase 2) encodes a rate-limiting enzyme involved in the de novo guanine nucleotide biosynthesis that catalyzes the NAD-dependent oxidation of inosine-5'-monophosphate (IMP) into xanthine-5'-monophosphate (XMP). It maintains the cellular guanine deoxy- and ribonucleotide pools that are required for the synthesis of DNA and RNA. It may be involved in some tumor progression and malignancy and may serve as a target for anticancer and immunosuppressive chemotherapy as it catalyzes an important step in purine nucleotide biosynthesis, which is necessary for the proliferation of lymphocytes.
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