ILF2 (interleukin enhancer binding factor 2) protein interacts with both DNA and RNA, and contains an N-terminal arginine- and glycine-rich domain at positions 3-22, and a zinc-finger DZF domain at positions 104-338. It is predominantly expressed in the testes.
Synonyms: Anti-Interleukin enhancer-binding factor 2 antibody produced in rabbit; Anti-Nuclear factor of activated T-cells 45 kDa antibody produced in rabbit
Storage: -20C
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Biochem Physiol Actions: ILF2 (interleukin enhancer binding factor 2) gene encodes a 45kDa transcription factor that forms a complex with the 90kDa interleukin enhancer-binding factor 3 (ILF3) and functions in regulation of genes at transcription, splicing, export, and translation levels. It has been identified as a component of the spliceosome. It is regulated by meiosis and associates with transcriptionally active chromatin. It also associates with RNAs in ribonucleoprotein complexes that are involved in the regulation of delayed translation of mRNAs. It facilitates T-cell transcription and expression of IL-2 gene. It plays a role in the encapsidation and protein priming of hepatitis B viral polymerase.
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