Synonyms: IL-15; MGC9721; OTTHUMP00000164616; OTTHUMP00000164617; interleukin 15
Storage: -20C
UNSPSC Code: 12352203
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General description: Interleukin-15 (IL-15) is an immunomodulating cytokine. The gene encoding it is localized on chromosome 4q31.
Biochem/physiol Actions: Interleukin-15 (IL-15) stimulates the proliferation of T lymphocytes and shares many biological properties with IL-2. It exerts its biological activities primarily on T cells. It is also essential in the development, survival and activation of NK cells. On binding to its receptor, IL-15 is indirectly involved in activating proto-oncogenes. Increased expression of IL-15 has been implicated with rheumatoid arthritis, inflammatory bowel disease, multiple sclerosis and diseases affiliated with retroviruses like human immunodeficiency virus (HIV) and human T-lymphotropic virus-1 (HTLV-I).
Immunogen: Peptide with sequence C-DATLYTESDVHPS, from the internal region of the protein sequence according to NP_000576.1; NP_751915.1
Physical form: Supplied at 0.5 mg/mL in 20mM Tris (pH 7.3) and 150mM NaCl with 0.02% sodium azide and 0.5% bovine serum albumin.
RIDADR: NONH for all modes of transport
WGK Germany: 2