IGSF9B (immunoglobulin superfamily, member 9B) is a member of the vertebrate immunoglobulin superfamily (IgSF). This family also includes immunoglobulin superfamily (IgSF), member 9 (IGSF9/Dasm1), which is a homologue of Drosophila protein Turtle. It is a hemophilic adhesion molecule, which is exclusively expressed in brain, especially in GABAergic interneurons. It has a C-terminal PDZ-binding domain, a transmembrane domain, five immunoglobulin (Ig) domains and two fibronectin III (FNIII) domains. It is predominantly localized at the inhibitory synapses.
Synonyms: Anti-CDNA FLJ40259 fis, clone TESTI2025486. antibody produced in rabbit; Anti-Fragment antibody produced in rabbit
Storage: -20C
Application: All Prestige Antibodies Powered by Atlas Antibodies are developed and validated by the Human Protein Atlas (HPA) project (www.proteinatlas.org)and as a result, are supported by the most extensive characterization in the industry. The Human Protein Atlas project can be subdivided into three efforts: Human Tissue Atlas, Cancer Atlas, and Human Cell Atlas. The antibodies that have been generated in support of the Tissue and Cancer Atlas projects have been tested by immunohistochemistry against hundreds of normal and disease tissues and through the recent efforts of the Human Cell Atlas project, many have been characterized by immunofluorescence to map the human proteome not only at the tissue level but now at the subcellular level. These images and the collection of this vast data set can be viewed on the Human Protein Atlas (HPA) site by clicking on the Image Gallery link. To view these protocols and other useful information about Prestige Antibodies and the HPA, visit sigma.com/prestige.
Biochem Physiol Actions: IGSF9B (immunoglobulin superfamily, member 9B) is involved in the development of inhibitory synapses, by binding to neuroligin 2, an inhibitory synaptic adhesion molecule.
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