HUWE1 is mapped on the human chromosome at Xp11.22. It has a molecular weight of 482 kDa.
Synonyms: Anti-ARF-BP1 antibody produced in rabbit; Anti-ARF-binding protein 1 antibody produced in rabbit; Anti-E3 ubiquitin-protein ligase HUWE1 antibody produced in rabbit; Anti-HECT, UBA and WWE domain-containing protein 1 antibody produced in rabbit; Anti-Mcl-1 ubiquitin ligase E3 antibody produced in rabbit; Anti-Mule antibody produced in rabbit; Anti-URE-B1 antibody produced in rabbit
Storage: -20C
Application: Anti-HUWE1 antibody produced in rabbit has been used to promote hexokinase 2's (HK2's) K63- linked ubiquitination.
Biochem Physiol Actions: HUWE1 is involved in base excision repair, cell proliferation and DNA damage response. The mutation in this gene is associated with Juberg-Marsidi and Brooks syndromes.
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