Synonyms: Anti-HMG box-containing protein 20A antibody produced in rabbit; Anti-HMG domain-containing protein HMGX1 antibody produced in rabbit; Anti-High mobility group protein 20A antibody produced in rabbit
Storage: -20C
Application: All Prestige Antibodies Powered by Atlas Antibodies are developed and validated by the Human Protein Atlas (HPA) project (www.proteinatlas.org)and as a result, are supported by the most extensive characterization in the industry. The Human Protein Atlas project can be subdivided into three efforts: Human Tissue Atlas, Cancer Atlas, and Human Cell Atlas. The antibodies that have been generated in support of the Tissue and Cancer Atlas projects have been tested by immunohistochemistry against hundreds of normal and disease tissues and through the recent efforts of the Human Cell Atlas project, many have been characterized by immunofluorescence to map the human proteome not only at the tissue level but now at the subcellular level. These images and the collection of this vast data set can be viewed on the Human Protein Atlas (HPA) site by clicking on the Image Gallery link. To view these protocols and other useful information about Prestige Antibodies and the HPA, visit sigma.com/prestige.
Biochem Physiol Actions: HMG20A (high mobility group 20A) gene encodes a HMG (High mobility group) box-containing protein that is involved in the activation of REST (RE-1 silencing transcription factor)-responsive genes. It functions in the initiation of neuronal differentiation. HMG proteins are non-histone proteins that are ubiquitously expressed. They are capable of binding to DNA and chromatin, and function in modulating the chromatin structure.
Legal Information: Prestige Antibodies is a registered trademark of Sigma-Aldrich Co. LLC