Gasdermin A (GSDMA) is located at 17q21.1 on the human chromosome. Its molecular weight is 49 kDa. GSDMA is localized in the pit cells of the gastric epithelium.
Synonyms: GSDM; GSDM1; GSDMA; Gasdermin-1; Gasdermin-A
Storage: -20C
Biochem Physiol Actions: Gasdermin A (GSDMA) plays a major role in regulating the tumor growth factor- ß (TGF-ß) and induces apoptosis. Mutation in this gene leads to gastric adenocarcinoma.