Synonyms: Anti-Grainyhead-like protein 1 homolog antibody produced in rabbit; Anti-Mammalian grainyhead antibody produced in rabbit; Anti-NH32 antibody produced in rabbit; Anti-Transcription factor CP2-like 2 antibody produced in rabbit; Anti-Transcription factor LBP-32 antibody produced in rabbit
Storage: -20C
Application: Anti-GRHL1 antibody produced in rabbit, a Prestige Antibody, is developed and validated by the Human Protein Atlas (HPA) project (www.proteinatlas.org). Each antibody is tested by immunohistochemistry against hundreds of normal and disease tissues. These images can be viewed on the Human Protein Atlas (HPA) site by clicking on the Image Gallery link. The antibodies are also tested using immunofluorescence and western blotting. To view these protocols and other useful information about Prestige Antibodies and the HPA, visit sigma.com/prestige.
Biochem Physiol Actions: Grainyhead-like 1 (GRHL1) is referred as MGR, NH32, LBP32 and TFCP2L2. This gene is critical for Drosophila neural development. Its overexpression in primary neuroblastomas is correlated on transcriptional and translational levels with favorable patient survival. It is an important regulator of the Dsg1 genes in the context of hair anchorage and epidermal differentiation.
Legal Information: Prestige Antibodies is a registered trademark of Sigma-Aldrich Co. LLC