alpha-D-Galactosidase A (GLA), a lysosomal enzyme, is a glycoside hydrolase that removes alpha-galactosyl moieties from glycolipid and glycoprotein glycans. Lack of GLA results in the accumulation of globotriaosylsphingosine (Gb3) in a variety of tissues resulting in the pathology called Fabry disease (FD).
Synonyms: Anti-alpha-D-Galactosidase A antibody produced in rabbit; Anti-alpha-D-Galactoside galactohydrolase antibody produced in rabbit; Anti-alpha-Galactosidase A precursor antibody produced in rabbit; Anti-Agalsidase alfa antibody produced in rabbit; Anti-Melibiase antibody produced in rabbit
Storage: -20C
Application: Rabbit polyclonal anti-GLA antibody is used to tag alpha-D-Galactosidase A for detection and quantitation by immunocytochemical and immunohistochemical (IHC) techniques. It is used as a probe to determine the presence and roles of alpha-D-Galactosidase A in glycan catabolism and Fabry disease.
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