Histone H2AX (H2A histone family member X), a histone variant present in almost all eukaryotes, is coded by H2AFX gene. It is mapped to human chromosome 11q23.2-11q23.3.
Synonyms: H2AX Ser139 p; Histone H2AX (phospho ser139)
Storage: -20C
Biochem Physiol Actions: H2AX (H2A histone family member X) helps to maintain genome stability. It plays an important role in localisation and structuring of the repair focus. H2AX also plays an active role in supplying the active repair proteins. ?H2AX participates in DSB repair. This protein serves as a signal and target of phosphorylation in the spreading phase.