G6PD gene is mapped to human chromosome Xq28, and spans 16.2kb. Its deficiency is highly hetereogenous, with around 190 variants being reported.
Synonyms: Anti-G-6-PDH antibody produced in rabbit; Anti-G6PDH antibody produced in rabbit; Anti-Glucose-6-phosphate dehydrogenase antibody produced in rabbit
MDL Number: MFCD00162329
Storage: -20C
Application: Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.Immunocytochemistry (1 paper)
Biochem Physiol Actions: Glucose-6-Phosphate Dehydrogenase (G6PD) deficiency is recessively inherited predominantly in males. Its activity shows statistical significant correlation with total bilirubin blood levels. G6PD suppression may help in the treatment strategies for inhibiting tumor progression and acts as a novel anti-hepatocellular carcinoma (HCC) target. Its deficiency is a common inherited enzyme defect (a disorder associated with acute or chronic hemolytic anemia). G6PD enzyme is responsible for the oxidation of glucose-6-phosphate, and thus, confers protection against oxidative damage in erythrocytes.
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