Fezf2 is a transcriptional repressor protein. It is required for the specification of corticospinal motor neurons and other subcerebral projection neurons. FeZf2 also plays a role in the layer and subcortical specific patterning of the subcortical projections and axonal fasciculations that develop in the brain. Fezf2 also controls the development of the dendritic arborization and spines of the large layer V pyramidal neurons. Thus biological processes involving Fezf2 include neuronal patterning, differentiation, neurogenesis, axon guidance, fasciculation, cortex development, anterior/posterior patterning, dendrite development, and locomotory behavior, and it was recently identified as a multipotent progenitor marker for neocortical projection neurons, astrocytes, and oligodendrocytes.
Synonyms: Fez family zinc finger protein 2, Forebrain embryonic zinc finger-like protein 2, Zinc finger protein 312, Zinc finger protein Fez-like
Application: This Anti-Fezf2 Antibody is validated for use in Western Blotting and Immunohistochemistry (Paraffin) for the detection of Fezf2.
Other Notes: Concentration: Please refer to lot specific datasheet.