Synonyms: Anti-Fcgamma-binding protein antigen antibody produced in rabbit; Anti-FcgammaBP antibody produced in rabbit; Anti-IgGFc-binding protein precursor antibody produced in rabbit
Storage: -20C
Application: Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.Immunofluorescence (1 paper)
Biochem Physiol Actions: IgGFc-binding protein is a protein encoded by the FCGBP gene in humans. The gene is also known as Fc?BP. Its mRNA is expressed only in placenta and colonic epithelial cells. It may play an important role in immune protection and inflammation in the intestines of primates. The gene is expressed in both human and mouse prostates. Differential expression of this gene could reflect its potential role in prostate malignancy as well as an indicator for progression of the cancer. It is differentially expressed in normal thyroid tissue, thyroid adenomas and thyroid carcinomas. The gene is constitutively expressed in normal thyroid tissue, its expression is significantly increased in follicular thyroid adenomas and considerably decreased in papillary and follicular thyroid carcinomas. The expression level of this gene in thyroid biopsies is useful for distinguishing between a thyroid follicular adenoma and a follicular carcinoma.
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