Fructose-1,6-bisphosphatase 1, is a homotetrameric protein, encoded by the gene mapped to human chromosome 9q22.
Synonyms: Anti-D-fructose-1,6- bisphosphate 1-phosphohydrolase 1; Anti-FBPase 1; Anti-Fructose-1,6-bisphosphatase 1
Storage: -20C
Application: Anti-FBP1 antibody produced in rabbit has been used in immunohistochemical staining and immunoblotting.
Biochem Physiol Actions: Mutation in the FBP1 gene is associated with clear cell renal cell carcinoma (ccRCC). Deficiency of this protein is an autosomal, recessively inherited disease that progresses with severe hypoglycemia and metabolic attacks result in a defect in gluconeogenesis.
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